Structural and Computational Glycobiology: Immunity and Infection
Author | : Elizabeth Yuriev |
Publisher | : Frontiers Media SA |
Total Pages | : 104 |
Release | : 2015-08-04 |
ISBN-10 | : 9782889196388 |
ISBN-13 | : 2889196380 |
Rating | : 4/5 (380 Downloads) |
Download or read book Structural and Computational Glycobiology: Immunity and Infection written by Elizabeth Yuriev and published by Frontiers Media SA. This book was released on 2015-08-04 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in understanding the biological role of carbohydrates has increased significantly over the last 20 years. The use of structural techniques to understand carbohydrate-protein recognition is still a relatively young area, but one that is of emerging importance. The high flexibility of carbohydrates significantly complicates the determination of high quality structures of their complexes with proteins. Specialized techniques are often required to understand the complexity of carbohydrate recognition by proteins. In this Research Topic, we will focus on structural and computational approaches to understanding carbohydrate recognition by proteins involved in immunity and infection. Particular areas of focus include cancer immunotherapeutics, carbohydrate-lectin interactions, glycosylation and glycosyltransferases.