Download or read book Moderately Proteinuric IgA Nephropathy in the Young written by Rosanna Coppo and published by IOS Press. This book was released on 2000 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: IgA nephropathy (IgAN) is one of the most common glomerular diseases world-wide. Its natural history is consistent with a clinical onset in the first decades of life. Clinical indicators of poor prognosis are proteinuria and hypertension. Angiotensin-converting enzyme-inhibitors (ACE-I) are a promising treatment, since angiotensin II playes a key role in glomerular hypertension and permselectivity and modulates mesangial and tubular cell functions.