Download or read book Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicals written by International Labour Organisation and published by World Health Organization. This book was released on 2006 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides an introduction to the field of transgenic mutagenicity assays and assesses the possible role of these assays in toxicology testing and mechanistic research. Part I gives a short overview of in vivo genotoxicity testing. Part II gives an overview of the data produced by various assays. Part III discusses the use of the assays in research. Part IV evaluates the role and potential added value of transgenic mutation assays in toxicology and risk assessment. This document is directed at toxicologists, research scientists and risk assessors.--Publisher's description.