Phosphodiesterase Inhibitors

Phosphodiesterase Inhibitors
Author :
Publisher : Elsevier
Total Pages : 247
Release :
ISBN-10 : 9780080538815
ISBN-13 : 0080538819
Rating : 4/5 (819 Downloads)

Book Synopsis Phosphodiesterase Inhibitors by :

Download or read book Phosphodiesterase Inhibitors written by and published by Elsevier. This book was released on 1996-08-16 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. - Utilizes actual testing and research of new PDE inhibitors - Valuable for researchers and students alike


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The activities of the Food and Nutrition Board's Committee on Military Nutrition Research (CMNR, the committee) have been supported since 1994 by grant DAMD17-9