Antigenic Variation

Antigenic Variation
Author :
Publisher : Elsevier
Total Pages : 461
Release :
ISBN-10 : 9780080475882
ISBN-13 : 0080475884
Rating : 4/5 (884 Downloads)

Book Synopsis Antigenic Variation by : Alister G. Craig

Download or read book Antigenic Variation written by Alister G. Craig and published by Elsevier. This book was released on 2003-08-20 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.Comprehensive coverage of antigenic variation from viruses to parasitesDiscussions devoted to molecular mechanisms of host evasionDetailed descriptions of host/pathogen interactions


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