A Network-Based Approach to Cell Metabolism

A Network-Based Approach to Cell Metabolism
Author :
Publisher : Springer
Total Pages : 162
Release :
ISBN-10 : 9783319640006
ISBN-13 : 3319640003
Rating : 4/5 (003 Downloads)

Book Synopsis A Network-Based Approach to Cell Metabolism by : Oriol Güell

Download or read book A Network-Based Approach to Cell Metabolism written by Oriol Güell and published by Springer. This book was released on 2017-08-16 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures. The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions. Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec ts of the networks themselves to the balance of biochemical fluxes.


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