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Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
Language: en
Pages: 16
Authors: OECD
Categories:
Type: BOOK - Published: 2011-07-28 - Publisher: OECD Publishing

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This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multip
Test No. 488
Language: en
Pages:
Authors:
Categories:
Type: BOOK - Published: 2013 - Publisher:

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
Language: en
Pages: 29
Authors: OECD
Categories:
Type: BOOK - Published: 2022-06-30 - Publisher: OECD Publishing

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This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations in somatic and germ cells. In this assay, transgenic rats o
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 471: Bacterial Reverse Mutation Test
Language: en
Pages: 12
Authors: OECD
Categories:
Type: BOOK - Published: 1997-07-21 - Publisher: OECD Publishing

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The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and Escherichia coli to detect point mutations by
Assessing Genetic Risks
Language: en
Pages: 353
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 1994-01-01 - Publisher: National Academies Press

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Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most