Structure-based Design of Drugs and Other Bioactive Molecules

Structure-based Design of Drugs and Other Bioactive Molecules
Author :
Publisher : John Wiley & Sons
Total Pages : 474
Release :
ISBN-10 : 9783527333653
ISBN-13 : 3527333657
Rating : 4/5 (657 Downloads)

Book Synopsis Structure-based Design of Drugs and Other Bioactive Molecules by : Arun K. Ghosh

Download or read book Structure-based Design of Drugs and Other Bioactive Molecules written by Arun K. Ghosh and published by John Wiley & Sons. This book was released on 2014-08-11 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design. This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.


Structure-based Design of Drugs and Other Bioactive Molecules Related Books

Structure-based Design of Drugs and Other Bioactive Molecules
Language: en
Pages: 474
Authors: Arun K. Ghosh
Categories: Medical
Type: BOOK - Published: 2014-08-11 - Publisher: John Wiley & Sons

GET EBOOK

Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medic
Structure-Based Drug Design
Language: en
Pages: 665
Authors: Pandi Veerapandian
Categories: Medical
Type: BOOK - Published: 2018-03-29 - Publisher: Routledge

GET EBOOK

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, t
Drug Design
Language: en
Pages: 289
Authors: Kenneth M. Merz
Categories: Medical
Type: BOOK - Published: 2010-05-31 - Publisher: Cambridge University Press

GET EBOOK

This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200
Structure-based Ligand Design, Volume 6
Language: en
Pages: 176
Authors: Klaus Gubernator
Categories: Science
Type: BOOK - Published: 1998-09 - Publisher: Wiley-VCH

GET EBOOK

"Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic paradigm of
Protein-Ligand Interactions
Language: de
Pages: 262
Authors: Hans-Joachim Böhm
Categories: Science
Type: BOOK - Published: 2006-03-06 - Publisher: John Wiley & Sons

GET EBOOK

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences.