Interactively Run Simulations and Experiment with Real or Simulated Data to Make Sequential Analysis Come AliveTaking an accessible, nonmathematical approach to

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim resul

A technically precise yet clear presentation of modern sequential methodologies having immediate applications to practical problems in the real world, Applied S

Monte Carlo methods are revolutionizing the on-line analysis of data in many fileds. They have made it possible to solve numerically many complex, non-standard

Sequential Experimentation in Clinical Trials: Design and Analysis is developed from decades of work in research groups, statistical pedagogy, and workshop part