Vascular smooth muscle cells (VSMC) populate the medial layer of blood vessels and are able to modulate their phenotype in response to environmental cues. Defin

Endothelial cell-dependent Notch signaling plays many critical roles in homeostasis and remodeling in the vasculature and serves an important role in the commun

The Notch signaling pathway has long been intricately linked with the development and function of the vasculature. In vascular smooth muscle cells (VSMCs), Notc

In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (S

Atherosclerosis is characterized by the narrowing of the arterial lumen termed "stenosis", due to the expansion of arterial plaques. One of the major contributi