This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to addr

The past three decades have witnessed an explosion of what is now referred to as high-dimensional `omics' data. Bioinformatics Methods: From Omics to Next Gener

This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the

The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young fiel