Providing a general guide to statistical methods used in the pharmaceutical industry, and illustrating how to use S-PLUS to implement these methods, the book ex

Each chapter consists of basic statistical theory, simple examples of S-PLUS code, plus more complex examples of S-PLUS code, and exercises. All data sets are t

The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theor

In a clear style the most important ideas of S-PLUS are introduced through the use of many examples. Each chapter includes a collection of exercises, fully work